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The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgment. nor any other party involved in the preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material.
A portion of the drug is excreted unchanged in the urine, while the rest is metabolized via the liver. V.: Treatment of moderate to severe allergic reactions: 5 mg/kg/day or 150 mg/m 2 /day in divided doses every 6-8 hours, not to exceed 300 mg/day Minor allergic rhinitis or motion sickness: 2 to /= 12 years: 25 mg every 4 hours; maximum 150 mg/day I. V.: Treatment of dystonic reactions: 0.5-1 mg/kg/dose Adults: Oral: 25-50 mg every 6-8 hours Minor allergic rhinitis or motion sickness: 25-50 mg every 4-6 hours; maximum: 300 mg/day Moderate to severe allergic reactions: 25-50 mg every 4 hours, not to exceed 400 mg/day Nighttime sleep aid: 50 mg at bedtime I. V.: 10-50 mg in a single dose every 2-4 hours, not to exceed 400 mg/day Dystonic reaction: 50 mg in a single dose; may repeat in 20-30 minutes if necessary Topical: For external application, not longer than 7 days Supplied Elixir, as hydrochloride: 12.5 mg/5 m L (480 m L) Caplet, as hydrochloride: 25 mg, 50 mg Capsule, as hydrochloride: 25 mg, 50 mg Injection, solution, as hydrochloride: 50 mg/m L (1 m L) Solution, topical, as hydrochloride [spray] (Benadryl® Itch Stopping Extra Strength): 2% (60 m L) [contains zinc acetate 0.1%] Tablet, chewable, as hydrochloride (Benadryl® Children's Allergy): 12.5 mg [contains phenylalanine 4.2 mg/tablet; grape flavor] Tablet, orally-disintegrating, as citrate (Benadryl® Children's Allergy Fastmelt®): 19 mg [equivalent to diphenhydramine hydrochloride 12.5 mg; contains phenylalanine 4.5 mg/tablet and soy protein isolate; cherry flavor] Adult (usual): Antiemetic: I. Anxiety: Oral: 25-100 mg 4 times/day; maximum: 600 mg/day. Anesthesia adjunct: 25-50 mg IM or IV prior to surgery. Nausea and vomiting: 12.5-25 mg orally ,rectally, IV or IM every 4 to 6 hrs. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER.
Detailed information on the pharmacokinetics of diphenhydramine hydrochloride injection is not available. Global RPH does not directly or indirectly practice medicine or provide medical services and therefore assumes no liability whatsoever of any kind for the information and data accessed through the Service or for any diagnosis or treatment made in reliance thereon.
Dosage - Oral: Children 6-11 years: 30 mg twice daily Children /= 6 years and Adults: 10 mg once daily Elderly: Peak plasma levels are increased; elimination half-life is slightly increased; specific dosing adjustments are not available Dosage adjustment in renal impairment: Clcr /= 6 years and Adults: 10 mg every other day Supplied Syrup (Claritin®): 1 mg/m L (120 m L) [contains sodium benzoate; fruit flavor] Tablet (Alavert™, Claritin®, Claritin® Hives Relief; Tavist® ND): 10 mg Tablet, rapidly-disintegrating: 10 mg Alavert™: 10 mg [contains phenylalanine 8.4 mg/tablet] Claritin® Redi Tabs®: 10 mg [mint flavor] Dimetapp® Children's ND: 10 mg [contains phenylalanine 8.4 mg/tablet] (pseudoephedrine 120mg fexofenadine 60mg). Bilastine is a new, well-tolerated, nonsedating H1 receptor antihistamine. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Mechanism of Action Cyproheptadine is a serotonin and histamine antagonist with anticholinergic and sedative effects.Antiserotonin and antihistamine drugs appear to compete with serotonin and histamine, respectively, for receptor sites.